Cambridge Healthtech Institute’s Inaugural
Advances in Immunoengineering
Modulating Immune Responses
11 November 2025
Cambridge Healthtech Institute's 8th Annual Advances in Immunoengineering conference offers insights into the field of immunoengineering, with breakthrough approaches in modulating immune responses in oncology and beyond. Join industry experts and researchers to discuss cutting-edge advances in immune cell engineering, tumour microenvironment targeting, spatial omics applications, and AI-driven immune modulation. This conference will provide a comprehensive look at engineering the next frontier in immunotherapeutics.
Coverage will include, but is not limited to:
Engineering the Next Wave of Immune Cell Engagers
- Masked CD3 approaches
- Using cytotoxic effects of T cells to target pathogenic B cells
- Complement pathway modulation strategies
- FcRn blockers and recycling mechanisms
- Enzyme-based IgG cleaving mechanisms
Computational and Machine Learning Approaches in T Cell Engineering
- AI in immunoepitope discovery and validation
- Generative AI approaches to build novel binders for CARs
- Computational modeling of immune cell interactions
- Single-cell multi-omics for immune cell engineering
- Computational modeling of T cell signaling networks, epitope prediction, and TCR design
Spatial Omics Application
- Applications of spatial omics to understand mechanisms of action
- Spatial omics for mapping immune-tumour interactions
- Understanding inflammatory mechanisms through spatial analysis
Tumour Microenvironment Modulation
- Tumour-immune biology in solid tumours (colorectal cancer, cholangiocarcinoma, hepatoblastoma)
- Microbiome influence in cancer treatments and prognosis
- Overcoming immune suppression and resistance
- Monitoring immune response to therapies
Addressing Resistance Mechanisms
- Overcoming T cell exhaustion in solid tumours
- Targeting immune suppressive myeloid populations
- Strategies to enhance CAR T cell persistence
- Addressing antigen escape in engineered cell therapies
The deadline for priority consideration is 28 March 2025.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: