The dynamics within the tumour microenvironment profoundly influences cancer progression, metastasis and response to therapy. At the Modulating the Tumour Microenvironment conference, we invite speakers to examine the intricacies of the tumour microenvironment and share their cutting-edge advancements that will further our understanding of this dynamic landscape. Topics include dissecting and targeting immune cells int he TME, understanding the role of neutrophils, prostanoids, CAFs, macrophages, etc in anti-tumor immunity and strategies to overcome resistance, as well as harnessing different immune cell populations to develop promising therapeutic approaches targeting the TME.